Publons users have indicated that they sit on Journal of Enzyme Inhibition and Medicinal Chemistry's editorial board but we are unable to verify these claims. We can put registered members of Publons' reviewer community in touch with partnered journals they would like to review for. The main protease of coronaviruses and the 3C protease of enteroviruses share a similar active-site architecture and a unique requirement for glutamine in the P1 position of the substrate. Enzyme Inhib. The acceptance rate of Journal of Enzyme Inhibition and Medicinal Chemistry is still under calculation. Chem. Abbreviation: Abbreviation 1: J. Enzym. Register a free Taylor & Francis Online account today to boost your research and gain these benefits: Register to receive personalised research and resources by email, Journal of Enzyme Inhibition and Medicinal Chemistry. An international and interdisciplinary open access journal, publishing new knowledge and findings on enzyme inhibitors and inhibitory processes, and agonist/antagonist receptor interactions in the development of medicinal and anti-cancer agents. To learn about our use of cookies and how you can manage your cookie settings, please see our Cookie Policy. By closing this message, you are consenting to our use of cookies. Journal of Enzyme Inhibition Abbreviation: J. The editor-in-chief is Claudiu T. Supuran. Design of selective COX-2 inhibitors in the (aza)indazole series. The Journal of Biochemical and Molecular Toxicology (JBMT) is an international journal (previously known as JBT) that has been in existence since 1986. The editor-in-chief is Claudiu T. Supuran. Inhibition of acetylcholinesterase and butyrylcholinesterase with uracil derivatives: kinetic and computational studies, Structure-guided design of anti-cancer ribonucleotide reductase inhibitors, New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases, Donepezil + chromone + melatonin hybrids as promising agents for Alzheimer’s disease therapy, Inhibition of protein phosphatase-1 and -2A by ellagitannins: structure-inhibitory potency relationships and influences on cellular systems, Chemical composition and enzyme inhibition of, Novel 2-indolinones containing a sulfonamide moiety as selective inhibitors of, Benzylamides and piperazinoarylamides of ibuprofen as fatty acid amide hydrolase inhibitors, Evaluation of a flavonoids library for inhibition of pancreatic α-amylase towards a structure–activity relationship, Computationally driven discovery of phenyl(piperazin-1-yl)methanone derivatives as reversible monoacylglycerol lipase (MAGL) inhibitors, 4-(3-Nitrophenyl)thiazol-2-ylhydrazone derivatives as antioxidants and selective hMAO-B inhibitors: synthesis, biological activity and computational analysis, Effect of cinnamamides on atopic dermatitis through regulation of IL-4 in CD4, Design and synthesis of 4-piperazinyl quinoline derived urea/thioureas for anti-breast cancer activity by a hybrid pharmacophore approach, Discovery of novel dual-active 3-(4-(dimethylamino)phenyl)-7-aminoalcoxy-coumarin as potent and selective acetylcholinesterase inhibitor and antioxidant, Development of a novel, high-affinity ssDNA trypsin inhibitor, Inhibition of α-, β-, γ-, δ-, ζ- and η-class carbonic anhydrases from bacteria, fungi, algae, diatoms and protozoans with famotidine, Synthesis and biological evaluation of 3-arylcoumarins as potential anti-Alzheimer's disease agents, Chemically stable inhibitors of 14-3-3 protein–protein interactions derived from BV02, Design, synthesis, and biological evaluation of novel derivatives of dithiodiglycolic acid prepared via oxidative coupling of thiols, Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3, Aberrant regulation favours matriptase proteolysis in neoplastic B-cells that co-express HAI-2, Evaluation of the anticancer potential of a sulphonamide carbonic anhydrase IX inhibitor on cervical cancer cells, Delivering bioactive cyclic peptides that target Hsp90 as prodrugs, Exploring the activity of polyamine analogues on polyamine and spermine oxidase: methoctramine, a potent and selective inhibitor of polyamine oxidase, Inhibition potential of phenolic constituents from the aerial parts of, Synthesis and biological evaluation of ursolic acid derivatives bearing triazole moieties as potential anti-, Novel Re(I) tricarbonyl coordination compounds based on 2-pyridyl-1,2,3-triazole derivatives bearing a 4-amino-substituted benzenesulfonamide arm: synthesis, crystal structure, computational studies and inhibitory activity against carbonic anhydrase I, II, and IX isoforms†, Osteopontin – a biomarker of disease, but also of stage stratification of the functional myocardial contractile deficit by chronic ischaemic heart disease, The protective role of jervine against radiation-induced gastrointestinal toxicity, CRISPR/Cas9-based liver-derived reporter cells for screening of mPGES-1 inhibitors, Discovery of novel coumarin derivatives as potent and orally bioavailable BRD4 inhibitors based on scaffold hopping, The antitumor activity of CYB-L10, a human topoisomerase IB catalytic inhibitor, New insight into structure-activity of furan-based salicylate synthase (MbtI) inhibitors as potential antitubercular agents, Design, synthesis, and apoptosis-promoting effect evaluation of novel pyrazole with benzo[, Novel thienopyrimidine derivatives as dual EGFR and VEGFR-2 inhibitors: design, synthesis, anticancer activity and effect on cell cycle profile, Sesquiterpenoids and 2-(2-phenylethyl)chromones respectively acting as α-glucosidase and tyrosinase inhibitors from agarwood of an, SAR and molecular mechanism studies of monoamine oxidase inhibition by selected chalcone analogs, Antioxidant activity and antibacterial evaluation of new thiazolin-4-one derivatives as potential tryptophanyl-tRNA synthetase inhibitors, Design, synthesis and molecular mechanisms of novel dual inhibitors of heat shock protein 90/phosphoinositide 3-kinase alpha (Hsp90/PI3Kα) against cutaneous melanoma, Evaluation of caffeine as inhibitor against collagenase, elastase and tyrosinase using, Benzonate derivatives of acetophenone as potent, Thermostability enhancement of the α-carbonic anhydrase from, Design, synthesis, and anticancer evaluation of novel quinoline derivatives of ursolic acid with hydrazide, oxadiazole, and thiadiazole moieties as potent MEK inhibitors, Probing the role of an invariant active site His in family GH1 β-glycosidases, Design, synthesis and biological activity evaluation of a new class of 2,4-thiazolidinedione compounds as insulin enhancers, Kinetic and computational molecular docking simulation study of novel kojic acid derivatives as anti-tyrosinase and antioxidant agents, A novel anti-platelet aggregation target of chinensinaphthol methyl ether and neojusticin B obtained from, Evaluation of the published kinase inhibitor set to identify multiple inhibitors of bacterial ATP-dependent mur ligases, Molecular modeling studies on the interactions of 7-methoxytacrine-4-pyridinealdoxime, 4-PA, 2-PAM, and obidoxime with VX-inhibited human acetylcholinesterase: a near attack conformation approach, Novel sulfonamide benzoquinazolinones as dual EGFR/HER2 inhibitors, apoptosis inducers and radiosensitizers, Impact of phytosterols on liver and distal colon metabolome in experimental murine colitis model: an explorative study, Structure-based design generated novel hydroxamic acid based preferential HDAC6 lead inhibitor with on-target cytotoxic activity against primary choroid plexus carcinoma, Stereoselective pharmacokinetic and pharmacodynamic analysis of a CNS-active sulphamoylphenyl carbamate derivative, Synthesis and biological evaluation of 3–(4-aminophenyl)-coumarin derivatives as potential anti-Alzheimer’s disease agents, Antiproliferative activity and p53 upregulation effects of chalcones on human breast cancer cells, Design, synthesis, molecular modelling, and biological evaluation of novel substituted pyrimidine derivatives as potential anticancer agents for hepatocellular carcinoma, Design and synthesis of novel pyrazolo[4,3-, Synthesis and characterisation of a new benzamide-containing nitrobenzoxadiazole as a GSTP1-1 inhibitor endowed with high stability to metabolic hydrolysis, Discovery and antitumor evaluation of novel inhibitors of spermine oxidase, Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interaction, Identification of phenazine analogue as a novel scaffold for thioredoxin reductase I inhibitors against Hep G2 cancer cell lines, Appraisal of anti-protozoan activity of nitroaromatic benzenesulfonamides inhibiting carbonic anhydrases from, Synthesis and biological evaluation of novel 8-substituted quinoline-2-carboxamides as carbonic anhydrase inhibitors, The first activation study of the β-carbonic anhydrases from the pathogenic bacteria, Seeking new approach for therapeutic treatment of cholera disease via inhibition of bacterial carbonic anhydrases: experimental and theoretical studies for sixteen benzenesulfonamide derivatives, Activation of human α-carbonic anhydrase isoforms I, II, IV and VII with bis-histamine schiff bases and bis-spinaceamine substituted derivatives, Synthesis of a new series of 3-functionalised-1-phenyl-1,2,3-triazole sulfamoylbenzamides as carbonic anhydrase I, II, IV and IX inhibitors, Synthesis, activity evaluation, and pro-apoptotic properties of novel 1,2,4-triazol-3-amine derivatives as potent anti-lung cancer agents, 1D NMR WaterLOGSY as an efficient method for fragment-based lead discovery, Synthesis, antiasthmatic, and insecticidal/antifungal activities of allosamidins, Discovery of aminopyridine-containing spiro derivatives as EGFR mutations inhibitors, Novel phthalimide based analogues: design, synthesis, biological evaluation, and molecular docking studies, Synthesis of substituted 15β-alkoxy estrone derivatives and their cofactor-dependent inhibitory effect on 17β-HSD1, Potential multifunctional agents with anti-hepatoma and anti-inflammation properties by inhibiting NF-кB activation, Non-covalent immunoproteasome inhibitors induce cell cycle arrest in multiple myeloma MM.1R cells, Computer-aided design and synthesis of 3-carbonyl-5-phenyl-1, Carbazole scaffolds in cancer therapy: a review from 2012 to 2018, Design and synthesis of phthalazine-based compounds as potent anticancer agents with potential antiangiogenic activity via VEGFR-2 inhibition, Discovery of new butyrylcholinesterase inhibitors via structure-based virtual screening, Anticancer sulfonamide hybrids that inhibit bladder cancer cells growth and migration as tubulin polymerisation inhibitors, New peptide derived antimalaria and antimicrobial agents bearing sulphonamide moiety, Design, synthesis and biological activity of selective hCAs inhibitors based on 2-(benzylsulfinyl)benzoic acid scaffold, Synthesis and enzyme-based evaluation of analogues, Dual and selective inhibitors of pteridine reductase 1 (PTR1) and dihydrofolate reductase-thymidylate synthase (DHFR-TS) from, Kinetic and thermodynamic characterisation of HIV-protease inhibitors against E35D↑G↑S mutant in the South African HIV-1 subtype C protease, Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamides as carbonic anhydrase isoforms I and II inhibitors, Design, synthesis and biological evaluation of N-substituted α-hydroxyimides and 1,2,3-oxathiazolidine-4-one-2,2-dioxides with anticonvulsant activity, Inhibitory effects of flavonoids isolated from, Dual-target anti-Alzheimer’s disease agents with both iron ion chelating and monoamine oxidase-B inhibitory activity, Exploring benzoxaborole derivatives as carbonic anhydrase inhibitors: a structural and computational analysis reveals their conformational variability as a tool to increase enzyme selectivity, Exploration of the residues modulating the catalytic features of human carbonic anhydrase XIII by a site-specific mutagenesis approach, Exploring new structural features of the 4-[(3-methyl-4-aryl-2,3-dihydro-1,3-thiazol-2-ylidene)amino]benzenesulphonamide scaffold for the inhibition of human carbonic anhydrases, Synthesis, computational studies, tyrosinase inhibitory kinetics and antimelanogenic activity of hydroxy substituted 2-[(4-acetylphenyl)amino]-2-oxoethyl derivatives, Towards discovery of novel scaffold with potent antiangiogenic activity; design, synthesis of pyridazine based compounds, impact of hinge interaction, and accessibility of their bioactive conformation on VEGFR-2 activities, Design and application of oral colon administration system, Design, synthesis, and biological evaluation of novel androst-17β-amide structurally related compounds as dual 5α-reductase inhibitors and androgen receptor antagonists, Synthesis and bioevaluation of novel steroidal isatin conjugates derived from epiandrosterone/androsterone, An overview of carbonic anhydrases and membrane channels of synoviocytes in inflamed joints, Competitive α-glucosidase inhibitors, dihydrobenzoxanthones, from the barks of, Novel tyrosinase inhibitory peptide with free radical scavenging ability, Exosomes in head and neck cancer.

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